Fall 2024 Seminar Schedule

Wednesday September 11: Transforming Cancer Informatics at Brown

Center for Clinical Cancer Informatics and Data Science (CCIDS) Speakers

Jeremy L. Warner MD, MS, FAMIA, FASCO is the founding Director of CCIDS, Associate Director of Data Science for the Legorreta Cancer Center, and Professor of Medicine and Professor Biostatistics at Brown University. 

Ece Uzun, MS, PhD, FAMIA is the founding Director of Clinical Bioinformatics at Lifespan, Associate Director of CCIDS, Associate Professor of Pathology and Laboratory Medicine at Brown University and Editor-in-Chief of JMIR Bioinformatics and Biotechnology. 

Sanjay Mishra, MS, PhD is a Research Associate of Medicine at Brown University, a Research Program Manager at the Lifespan Cancer Institute, and the coordinator of CCIDS and the COVID-19 and Cancer Consortium (CCC19).

Abstract: The Brown Center for Clinical Cancer Informatics and Data Science (CCIDS) aims to 1) lead and collaborate in the development of standards for clinical cancer informatics and genomics; 2) to demonstrate and improve best practices in interoperability of the local data ecosystem that aligns with clinician and bioinformatician workflows; 3) to develop best-in-class natural language processing (NLP) solutions for cancer phenotyping at scale; 4) to cultivate machine-learning based models to predict cancer status using patient data; 5) to identify and promote rapid translational innovations; and 6) train next generation of clinicians and basic researchers in the domain of clinical cancer informatics through collaboration with stakeholders across Lifespan and Brown University, and the national organizations. In this seminar, we will introduce CCIDS and share our current research activities, seminar series and future plans.

Wednesday, September 25: Title & Abstract TBA.

Hamish Fraser MBChB, MSc, FACMI, FIASHI; Associate Professor of Medical Science, Brown Center for Biomedical Informatics, Warren Alpert Medical School, and Associate Professor of Health Services, Policy and Practice, School of Public Health, Brown University 

Hosted by Ritambhara Singh, John E. Savage Assistant Professor of Computer Science and Data Science.

Wednesday, October 9: Inferring gene regulatory network dynamics that control cell fate in single cells

Adam MacLean, PhD; Assistant Professor of Quantitative and Computational Biology, University of Southern California

Hosted by Ritambhara Singh, John E. Savage Assistant Professor of Computer Science and Data Science.

Abstract: Cells make decisions to enable multicellular life. Cell fate decision-making underlies development and homeostasis, and goes awry as we age. Despite great promise, we have yet to harness the high-resolution information on cell states and fates that single-cell genomics data offer to understand cell fate decisions in development and aging. Nor do we know how these fate decisions are controlled by gene regulatory networks. I will describe our recently developed methods for gene regulatory network inference using single-cell multiomics to infer dynamic cell state transitions. We have also constructed models of cell fate decisions in stem cells to discover how early-life events – mutational, transcriptional, and epigenetic – shape and change stem cell function as we age in a manner that could be harnessed to ameliorate diseases of aging.

Wednesday, October 23: Title & Abstract TBA.

Galip Gürkan Yardimci; Assistant Professor, CEDAR, OHSU Knight Cancer Institute

Hosted by Ritambhara Singh, John E. Savage Assistant Professor of Computer Science and Data Science.

Wednesday, November 6: Title & Abstract TBA.

Derek Aguiar, PhD; Associate Professor in the Department of Computer Science and Engineering, University of Connecticut 

Hosted by Roberta De Vito, Thomas J. and Alice M. Tisch Assistant Professor of Biostatistics and Data Science.

Wednesday, November 20: Title & Abstract TBA.

Laurits Skov, Ph.D.; Assistant Professor, Section for Evolutionary Genomics, Globe Institute, University of Copenhagen, Copenhagen, Denmark.

Hosted by Emilia Huerta-Sanchez, Associate Professor of Ecology, Evolution, and Organismal Biology. 

Wednesday, December 4: Title & Abstract TBA.

Kevin Lin, Assistant Professor, Biostatistics, University of Washington.

Hosted by Zhijin Wu, Professor of Biostatistics, Brown